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Spach, MD Editor-in-Chief Professor of Medicine Division of Allergy & Infectious Diseases University of Washington Disclosures : None Learning Objective Performance Indicators Provide rationale for choosing an oral antiviral versus interferon-based therapy to treat chronic hepatitis B virus (HBV) infection Choose an effective preferred oral antiviral for initial treatment of chronic HBV infection Recognize potential adverse effects with medications used to treat chronic HBV infection Describe special clinical circumstances that require modification of standard treatment options for chronic HBV infection Identify clinical situations in which interferon-based therapy is contraindicated for the treatment of chronic HBV infection Background In the United States, the Food and Drug Administration (FDA) has approved a total of eight medications to treat chronic hepatitis B virus (HBV) infection (Figure 1)

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References Khan, M